Menu
Menu
Menu
Menu
Menu
Menu
Menu
Menu
Menu
Opt
Routine
Expect
Good

Know More
Key Facts
FAQ's
Technical Presentation
Research
Menu
 
References:
1 Waterman, A. Accidental hypothermia during anaesthesia in dogs and cats Vet Rec. 1975, 96: 308-313.
2 Consequences of inadvertent perioperative hypothermia.
Doufas AG. Best Pract Res Clin Anaesthesiol. 2003 Dec;17(4):535-49. Review.

 

Alfaxan® top tips

You and your practice staff face the day-to-day challenges of running a busy operating theatre, routinely premedicating and anaesthetising your patients for surgery or other, less invasive, procedures.

We at Vetoquinol recognise the complexity of your routine tasks and have, therefore, created this guide with only one purpose in mind - to make your experience of Alfaxan® as easy, pleasant and simple as possible. This document is a product of joint efforts of a number of leading UK anaesthesia experts and Vetoquinol’s veterinary services team. Its aim is to help you and your colleagues optimise the way in which you use Alfaxan® to anaesthetise your patients every day.

We sincerely hope that this guide will make your daily Alfaxan® routine an enjoyable one and maximise your confidence and trust in the product.


Premedication Phase:
How to optimise the effect of your premeds
Good and effective premedication is paramount to the overall quality of anaesthesia and a good protocol is paramount to a smooth and uneventful recovery. The ideal premedication should:
1. Calm the patient - reduce stress and aid handling
2. Provide appropriate analgesia
3. Reduce the dose of induction and maintenance agents
4. Premedicate the patients according to their clinical requirements (weight should not be the only factor; different agents and dosages may be needed to provide adequate premedication)
5. Premedicate animals in relation to the planned induction time (avoiding blanket premedication on admittance)
6. Adhere to manufacturers’ recommendations. Route of administration can make a large difference to systemic absorption and effect

Induction of anaesthesia:
How to get the best out of your routine use of Alfaxan®
When you use Alfaxan® routinely, it is vital to be aware that induction can differ from other agents:
1. Premedication choice will affect the dose of Alfaxan® needed
 
We advise that when you first use Alfaxan® please inject the full dose (unless using an alpha-2-agonist* as a premedicant) slowly, over 60 seconds to minimise the risk of induction apnoea
2. An animal anaesthetised with Alfaxan® will be sedated very soon after you commence injecting
 
You may be tempted to stop injecting and attempt intubation too soon if deep sedation is mistaken for anaesthesia
Check eye position, blink reflex and jaw tone to assess depth of anaesthesia
3. Under-dosing may result in a reduced period of general anaesthesia caused by Alfaxan® which may not be long enough for the animals to adequately undergo the ‘transition’ from anaesthesia caused by the injectable agent to that caused by the inhalational agent. As a result, animals may appear very light or even regain consciousness
4. When you become more familiar with Alfaxan® you may find that anaesthetic depth is achieved at less than the total calculated dose (depending upon the chosen premedication regime).
 

* Please contact the Alfaxan® Technical support line for more information


Post induction phase:
What to expect after administering Alfaxan®
Immediately post induction there are some differences to other agents to be aware of:
1. Respiratory rates may be slightly increased and the tidal volume may be larger than with other anaesthetics
2. Heart rate may be higher than you are used to due to a physiological baroreceptor response to maintain cardiac output (and thus perfusion)
 
This is a positive aspect of Alfaxan® anaesthesia and care should be taken not to misinterpret this as insufficient anaesthetic depth. Check anaesthetic depth using eye position, blink reflex and jaw tone

Anaesthetic recovery:
How to achieve good quality recoveries
Alfaxan® is a short-acting induction agent and so recoveries should be smooth and rapid with a quick return to normal mentation. Because recoveries can be rapid:
1. Turn off volatile agents after any surgical stimulus has ended
2. For minimum stimulation during the recovery period it is recommended to move patients to recovery facilities as soon as possible after surgery is finished
3. Leave animals to recover in calm, warm and quiet surroundings
4. Ensure adequate analgesia in recovery
5. Monitor temperature until normothermic:
 
Hypothermia:
  Is very common in recovery (in a 10kg animal an hour long anaesthetic procedure can drop body temperature by 3-4 degrees Celsius)1
  Will cause shivering, which will increase pain at the surgical site and may prolong recovery
  Has been shown to increase the risk of post-operative wound infections2
  Has been shown to increase intra-operative bleeding2
 

This site is intended for the use of veterinary surgeons and veterinary nurses working within the UK. Alfaxan® contains alfaxalone 10mg/ml.  Legal category: POM-V.  Alfaxan® is a trademark of Jurox Pty Limited, Rutherford, NSW 2320, Australia. Further information is available on request  from Vetoquinol UK Limited, Vetoquinol House, Great Slade, Buckingham Industrial Park, Buckingham, MK18 1PA.

Click here to download the Alfaxan® SPC