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Dosage

Take a Minute!

At induction, IV injection speed should result in the total dose, if required, being administered over a period of 60 seconds.

Induction Dose Recommendations

Administer one quarter of the calculated dose every fifteen seconds, until the patient can be intubated. Premedication may result in significant dose requirement reduction.

Cats

Un-Premedicated Premedicated
5 mg/kg 5 mg/kg
0.5 mL/kg 0.5 mL/kg

Dogs

Un-Premedicated Premedicated
3 mg/kg 2 mg/kg
0.3 mL/kg 0.2 mL/kg

Maintenance Dose Recommendations

Maintenance doses of Alfaxan® can be given as supplemental boluses or by constant rate infusion. Administration rates should be manipulated to provide an adequate plane of anaesthesia for the procedure being performed.

Cats

Un-Premedicated Premedicated
Dose for constant rate infusion
10 - 11 mg/kg/hour 7 - 8 mg/kg/hour
0.16 - 0.18 mg/kg/minute 0.11 - 0.13 mg/kg/minute
0.016 - 0.018 mL/kg/minute 0.011 - 0.013 mL/kg/minute
Bolus dose for each 10 minutes maintenance
1.6 - 1.8 mg/kg 1.1 - 1.3 mg/kg
0.16 - 0.18 mL/kg 0.11 - 0.13 mL/kg

Dogs

Un-Premedicated Premedicated
Dose for constant rate infusion
8 - 9 mg/kg/hour 6 - 7 mg/kg/hour
0.13 - 0.15 mg/kg/minute 0.10 - 0.12 mg/kg/minute
0.013 - 0.015 mL/kg/minute 0.010 - 0.012 mL/kg/minute
Bolus dose for each 10 minutes maintenance
1.3 - 1.5 mg/kg 1.0 - 1.2 mg/kg
0.13 - 0.15 mL/kg 0.10 - 0.12 mL/kg