Induction Dose Recommendations
Dogs and Cats
Administer one quarter of the calculated dose every fifteen seconds, until the patient can be intubated. Premedication may result in significant dose requirement reduction.
Cat Induction Dose
| Un-Premedicated | Premedicated |
| 5 mg/kg | 5 mg/kg |
| 0.5 mL/kg | 0.5 mL/kg |
Dog Induction Dose
| Un-Premedicated | Premedicated |
| 3 mg/kg | 2 mg/kg |
| 0.3 mL/kg | 0.2 mL/kg |
Take a minute
At induction, IV injection speed should result in the total dose, if required, being administered over a period of 60 seconds.
Take a minute
At induction, IV injection speed should result in the total dose, if required, being administered over a period of 60 seconds.
Pet Rabbits
Rabbit Induction Dose
Recommended dose: 2mg/kg*
* This is lower than the labelled (SPC) premedicated dose for Alfaxan® Multidose and the dose may be further reduced if alpha-2 agonists or acepromazine have been administered.
Preoxygenation is essential
Administer one quarter of the calculated dose every 20-25 seconds flushing the intravenous cannula after each increment. Continue until stage III anaesthesia has been achieved.
Dose Calculator To calculate the maximum expected Alfaxan dose required in a premedicated animal enter the weight of the patient in kilograms, select the species and the rest is done for you.
0 mL
Maximum Dog dose
Maintenance
Maintenance doses of Alfaxan® Multidose in dogs and cats can be given as supplemental boluses or by constant rate infusion. Administration rates should be manipulated to provide an adequate plane of anaesthesia for the procedure being performed.
Cat Maintenance Dose
| Un-Premedicated | Premedicated |
| Dose for constant rate infusion | |
| 10 - 11 mg/kg/hour | 7 - 8 mg/kg/hour |
| 0.16 - 0.18 mg/kg/min | 0.11 - 0.13 mg/kg/min |
| 0.016 - 0.018 mL/kg/min | 0.011 - 0.013 mL/kg/min |
| Bolus dose for each 10 minutes maintenance | |
| 1.6 - 1.8 mg/kg | 1.1 - 1.3 mg/kg |
| 0.16 - 0.18 mL/kg | 0.11 - 0.13 mL/kg |
Dog Maintenance Dose
| Un-Premedicated | Premedicated |
| Dose for constant rate infusion | |
| 8 - 9 mg/kg/hour | 6 - 7 mg/kg/hour |
| 0.13 - 0.15 mg/kg/min | 0.10 - 0.12 mg/kg/min |
| 0.013 - 0.015 mL/kg/min | 0.010 - 0.012 mL/kg/min |
| Bolus dose for each 10 minutes maintenance | |
| 1.3 - 1.5 mg/kg | 1.0 - 1.2 mg/kg |
| 0.13 - 0.15 mL/kg | 0.10 - 0.12 mL/kg |
Resources
COSHH Data Sheet for Alfaxan® Multidose for dogs, cats and pet rabbits
The COSHH data sheet for your records
Alfaxan® Multidose Summary of Product Characteristics
The Alfaxan Multidose Data Sheet - a summary of the SPC
